Northern Institute for Cancer Research

Staff Profile

Maria Georgiou

Research Technician

Background

In 2016, I have received my BSc (Hons) in Biomedical Science from the University of Hull. During my degree, my final year project was based on the identification of significantly different miRNAs between two microarray data sets, between Oesophageal adenocarcinoma patient tumours that responded and non-responders to chemotherapy (CT), and between radiosensitive and radioresistant OE33 cell lines. Based on the common significantly different miRNAs, a candidate miRNA known as MiRNA26a was selected for validation using a qPCR. The results indicated that MiRNA26a regulates tumour sensitivity to chemoradiotherapy in oesophageal adenocarcinoma.

Thereafter, I have received my research Masters on Cancer from Newcastle University, where my research was focused on melanoma. Specifically, I was looking for the effects of CD271 inhibitors on melanoma cell viability and invasion using MTS microarray and scratch assay respectively.

Currently I am  a research technician funded by the Claire Coiley Trust,  in the Newcastle Sarcoma Research Group at the Northern Institute for Cancer Research (NICR) in Dr Kenneth Rankin's  Group. My project is focusing on Osteosarcoma circulating tumour cells and tissue sequencing. Specifically the project includes analysis of clinical blood samples using established molecular biology and antibody based methods including the evaluation of membrane bound matrix matalloproteinases as biomarkers in osteosarcoma.